The Relationship between Non-neurologic Organ Dysfunction with Outcome in Severe Traumatic Brain Injury (TBI)

Abstract

Background: One of the major complications resulting from head trauma is failure or dysfunction of vital body organs which has a remarkable effect on rate of mortality after brain injury due to trauma.

Materials and Methods: This descriptive-analytical study was performed on all patients hospitalized in General ICU, NICU and Trauma Ward of Poursina Hospital with 8 ≥GCS). Patients were divided into two groups of dead and survived in terms of outcome. Then, the variables of age, sex, length of ICU stay, mean score of MODS (Multiple Organ Dysfunction Score), and mean GCS were analyzed using SPSS16 software and Logistic Regression analysis and Correlation analysis.

Results: This study showed that respiratory dysfunction was the most common complication after severe head trauma. It reached to 68% on the sixth day after admission. The incidence of renal failure during hospitalization was 4% with 75% death rate.  The relationship between platelet counts with patient outcome based on three-month GOS was significant on the fifth and seventh days. The occurrence of liver dysfunction after severe trauma had a significant relationship with increased length of hospital stay and increased mortality. A strong correlation was found between non-neurologic organ dysfunction and patient’s outcome in severe brain injury.

Conclusion: This study indicated the incidence of non-neurologic organ dysfunction in patients having severe brain trauma with increased adverse outcome and emphasizes the importance of early diagnosis and decisive measures to minimize the adverse impact of these outcomes in these patient.