Study of relationship between clinical factors and velopharyngeal closure in cleft palate patients

Abstract

• BACKGROUND: This study was carried out to analyze the relationship between clinical factors and velopharyngeal closure (VPC) in cleft palate patients.
• METHODS: Chi-square test was used to compare the postoperative velopharyngeal closure rate. Logistic regression model was used to analyze independent variables associated with velopharyngeal closure.
• RESULTS: Difference of postoperative VPC rate in different cleft types, operative ages and surgical techniques was significant (P=0.000). Results of logistic regression analysis suggested that when operative age was beyond deciduous dentition stage, or cleft palate type was complete, or just had undergone a simple palatoplasty without levator, patients would suffer a higher velopharyngeal insufficiency rate after primary palatal repair.
• CONCLUSIONS: Cleft type, operative age and surgical technique were the contributing factors influencing VPC rate after primary palatal repair of cleft palate patients.
• KEYWORDS: Cleft Palate, Velopharyngeal Closure, Clinical Factor, Analysis.