Journal of Research in Medical Sciences1735-199516720110714Study of relationship between clinical factors and velopharyngeal closure in cleft palate patients70857085ENQiChenQianZhengBingShiHengYinTianMengGuang-ningZhengProfessor, Department of Radiology, West China Stomatological Hospital, Sichuan University, Chengdu, PR China.. gnzheng@163.com2011041420110613BACKGROUND: This study was carried out to analyze the relationship between clinical factors and velopharyngeal closure (VPC) in cleft palate patients.METHODS: Chi-square test was used to compare the postoperative velopharyngeal closure rate. Logistic regression model was used to analyze independent variables associated with velopharyngeal closure.RESULTS: Difference of postoperative VPC rate in different cleft types, operative ages and surgical techniques was significant (P=0.000). Results of logistic regression analysis suggested that when operative age was beyond deciduous dentition stage, or cleft palate type was complete, or just had undergone a simple palatoplasty without levator, patients would suffer a higher velopharyngeal insufficiency rate after primary palatal repair.CONCLUSIONS: Cleft type, operative age and surgical technique were the contributing factors influencing VPC rate after primary palatal repair of cleft palate patients.KEYWORDS: Cleft Palate, Velopharyngeal Closure, Clinical Factor, Analysis.