Soft tissue augmentation by autologous cultured fibroblasts transplantation for treatment of wrinkles and scars: a case series of 20 patients

Mohammad ali Nilforoushzadeh, Amir hosein Siadat, Mojgan Arian Rad, Fariba Moulavi, Elaheh Haftbaradaran, Mohammad hosein Nasr Esfahani

Abstract


  • BACKGROUND: There are many filler agents for augmentation of static wrinkles and atrophic scars from synthetic, biosynthetic, cadaver, animal and human sources.
  • METHODS: The current study presents 20 patients whose facial wrinkles and lines were treated by transplantation of autologous cultured fibroblasts. The fibroblast nature of cells was confirmed by immune-staining and flow cytometry.
  • RESULTS: The mean of improvement for this procedure at the 6 month follow up was 41%.
  • CONCLUSIONS: In conclusion autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars.
  • KEYWORDS: Soft Tissue Augmentation, Fibroblast, Wrinkle

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