Preoperative carbohydrate nutrition reduces postoperative nausea and vomiting compared to preoperative fasting

Neslihan Yilmaz, Nedim Çekmen, Ferruh Bilgin, Ela Erten, Mehmet Ozgür Ozhan, Ahmet Coşar


Background: The aim of this prospective, randomized, single-blinded study was to compare the effects of a carbohydrate drink 400
mL given 2 h before the surgery with preoperative overnight fasting on the gastric pH and residual volume, postoperative nausea
and vomiting (PONV) and antiemetic consumption in patients undergoing laparoscopic cholecystectomy. Materials And Methods:
Forty American Society of Anesthesiologists physical status I-II patients who underwent elective laparoscopic cholecystectomy.
Randomized, prospective, controlled study, Gulhane Medical Faculty and Guven Hospital Department of Anesthesiology and
Reanimation. Patients were randomly assigned into two groups: Pre-operative carbohydrate drink group (group C, n = 20) and
preoperative fasting group (group F, n = 20). Group C was given a 400 mL carbohydrate drink 2 h before to the surgery. The patients
of group F were fasted 8 h before the surgery. Both groups were operated under general anesthesia with volatile anesthetics. Results:
Hemodynamic parameters, demographic data, gastric acidity and residual volumes were similar for both groups. No complications
were observed. PONV and antiemetic consumption was lower in group C compared to group F (P = 0.001). Patient’s satisfaction
was higher in group C (P < 0.001). Conclusion: This study showed that pre-operative carbohydrate drink may be used safely and
also improves patient’s satisfaction and comfort in patients undergoing laparoscopic cholecystectomy.

Key words: Laparoscopic cholecystectomy, post-operative nausea and vomiting, pre-operative carbohydrate nutrition, pre-operative fasting

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