HEPARIN THERAPY IN PATIENT WITH NON-Q WAVE MYOCARDIAL INFARCTION AND UNSTABLE ANGINA
Abstract
Introduction. This study was conducted to find that, is there any advantage from (5000 IU/6h) in patient with non-Q wave MI and unastable angina.
Methods. In a randomized clinical trial two group of patients with non-Q wave MI and unstable angina were compared about their prognosis and management outcomes. In interventional group (n= 145), heparin (5000 IU/6h) was administered and in another group (n= 133) no treatment with heparin was used. Duration of chest pain, recurrent angina, intrahospital mortality were indices for patients outcome study.
Findings. Anticoagulant complication was not report in any patient in interventional group. There is no significant difference between two groups about prognosis factors.
Conclusion. Heparin administration (5000 IU/6h) may have not any role in improving management outcome in patient with non-Q wave MI and unastable angina at least in acute phase. So, it is recommended that heparin have been administered to these patients in continuous regimen (1000-1500 U/hour continuously effusion).
Methods. In a randomized clinical trial two group of patients with non-Q wave MI and unstable angina were compared about their prognosis and management outcomes. In interventional group (n= 145), heparin (5000 IU/6h) was administered and in another group (n= 133) no treatment with heparin was used. Duration of chest pain, recurrent angina, intrahospital mortality were indices for patients outcome study.
Findings. Anticoagulant complication was not report in any patient in interventional group. There is no significant difference between two groups about prognosis factors.
Conclusion. Heparin administration (5000 IU/6h) may have not any role in improving management outcome in patient with non-Q wave MI and unastable angina at least in acute phase. So, it is recommended that heparin have been administered to these patients in continuous regimen (1000-1500 U/hour continuously effusion).
Keywords
Heparin therapy, Non-Q wave MI, Unstable Angina, Administratio -Rout