GOITER SURVEY AND URINARY IODINE CONCENTRATION IN SCHOOLCHILDREN AGED 8 TO 10 YEAR OF ISFAHAN PROVINCE IN 1996
Abstract
Introduction: Iodine deficiency disorders (IDD) is a worldwide health problem. Many parts of the Islamic Republic of Iran had been known as areas of endemic goiter. IDD was accepted as a priority health problem in the country, and a National lDD council was formed in 1989 under the supervision of the Ministry of Health and Medical Education. One of the main strategies of National council for IDD control was to provid at least 150 g of iodine per day to the entire population through making available iodized salt. This study was performed to evaluate the national IDD council program in 1996, in rural and urban areas of Isfahan province.
Methods: One thousand and four hundred schoolchildren, aged 8 to 10 year, including 50% girls and 500k boys, were selected through random sampling. Grading of goiter was performed according to WHO"s classification. Serum T3. T 4 and TSH were measured by RIA and uninary iodine by digestion method.
Results: The mean of serum T 4. T3 and TSH were 10.2±1.7 µgldl, 166±97 ngldl and 2.7±0.8 µlu/ml, respectively. There were no difference between males and females and schoolchildren of rural and urban areas. 0.6 percent had serum T4 more than 12.5 µg/dl and eight person had TSH more thans 5 µlu/ml. The median urinary iodine was 21 µg/dl in entire population, 76 percent had urinary iodine more than 10 µg/dl. Only 10 percent had urinary iodine less than 5 µg/dl. Total prevalence of goiter was 58 percent (60 percent in girls and 53 percent in boys).
Disussion: Based on the available data, seven years after generalized use of iodized salt and 2 years after more than 50 percent of pupulation used iodized salt, uninary iodine of school children in Isfahan province showed sufficient iodine intake. However goiter is still hyperendemic in Isfahan province.
Methods: One thousand and four hundred schoolchildren, aged 8 to 10 year, including 50% girls and 500k boys, were selected through random sampling. Grading of goiter was performed according to WHO"s classification. Serum T3. T 4 and TSH were measured by RIA and uninary iodine by digestion method.
Results: The mean of serum T 4. T3 and TSH were 10.2±1.7 µgldl, 166±97 ngldl and 2.7±0.8 µlu/ml, respectively. There were no difference between males and females and schoolchildren of rural and urban areas. 0.6 percent had serum T4 more than 12.5 µg/dl and eight person had TSH more thans 5 µlu/ml. The median urinary iodine was 21 µg/dl in entire population, 76 percent had urinary iodine more than 10 µg/dl. Only 10 percent had urinary iodine less than 5 µg/dl. Total prevalence of goiter was 58 percent (60 percent in girls and 53 percent in boys).
Disussion: Based on the available data, seven years after generalized use of iodized salt and 2 years after more than 50 percent of pupulation used iodized salt, uninary iodine of school children in Isfahan province showed sufficient iodine intake. However goiter is still hyperendemic in Isfahan province.
Keywords
Iodine deficiency disorders, Goiter, Prevalence study, Isfahan, Children, Urine Iodine, Thyroid Hormon