Antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan, Iran

Hajarsadat Sadeghi, Tahmineh Narimani, Elham Tabesh, Fatemeh Shafiee, Rasool Soltani

Abstract


Background: The objective of this study was to evaluate the antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan province.

Materials and Methods: Gastric antrum biopsy specimens of patients undergoing endoscopy were cultured. The samples with the growth of H. pylori underwent antibiotic susceptibility test by disk diffusion method.

Reaults: Of 96 samples, 50 samples (53%) were positive for H. pylori. The rates of antibiotic resistance were as follows: amoxicillin, 6%;  zithromycin, 20%; furazolidone, 22%; levofloxacin, 16%; metronidazole,  0%; rifampin, 12%; and tetracycline, 22%. Conclusion: H. pylori strains
in our area have high rates of resistance to azithromycin, levofloxacin,  etronidazole, tetracycline, and furazolidone.


Keywords


Antibiotic, Helicobacter pylori, Patient, Resistance

Full Text:

PDF