Journal of Research in Medical Sciences 2018. 23(4):J Res Med Sci 2018, 23:33 (26 April 2018).

Effect of chamomile capsule on lipid? and hormonal?related parameters among women of reproductive age with polycystic ovary syndrome
Maryam Heidary, Zahra Yazdanpanahi, Mohammad Hossain Dabbaghmanesh, Mohammad Ebrahin Parsanezhad, Masoumeh Emamghoreishi, Marzieh Akbarzadeh

Abstract


Background: According to traditional herbal medicine, chamomile has been considered as one of the herbal remedies for patients with polycystic ovary syndrome (PCOS). Te study aimed to investigate the e?ect of chamomile on lipid and hormonal parameters in women of reproductive age with PCOS. Materials and Methods: Tis study is a  randomized clinical trial which was conducted on 80 women (40 patients in each group) of childbearing age with PCO. Te intervention group received 370 mg oral capsules of chamomile three times a day for 3 months. Te control group did receive starch capsule (three times a day). Hormonal and lipid parameters were examined before and 3 months after the intervention. Results: Te mean age of the patients was 22.40 ± 5.10
and 24.38 ± 6.14 years in the intervention and control groups,  espectively. Decreased level of testosterone was observed in the intervention group (in women with PCOS) who received chamomile capsules (P = 0.017). A signifcant di?erence was not seen in low?density lipoprotein cholesterol level (P = 0.249), high?density lipoprotein cholesterol (P = 0.073), triglycerides (P = 0.603), the hormone dehydroepiandrosterone sulfate (P = 0.423), and the ratio of luteinizing hormone/follicle?stimulating hormone (LH/FSH) in the experimental and control groups after the intervention (P = 0.420). Conclusion: According to the fndings, oral administration of chamomile capsule caused a signifcant decrease in total testosterone levels in these patients. However, no  signifcant change was
reported with lipid parameters, the ratio of LH/FSH, and dehydroepiandrosterone sulfate level.


Keywords


Chamomile herb, dyslipidemia, hirsutism, polycystic ovary syndrome

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