Evaluating the efficacy of mixture of Boswellia carterii, Zingiber officinale, and Achillea millefolium on severity of symptoms, anxiety, and depression in irritable bowel syndrome patients

Journal of Research in Medical Sciences1735-1995221120171203Evaluating the efficacy of mixture of Boswellia carterii, Zingiber officinale, and Achillea millefolium on severity of symptoms, anxiety, and depression in irritable bowel syndrome patients1072610726EN20171115Background: Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorders (FGIDs) that a?ects in<table class="NormalTable"><tbody><tr><td width="550">di?erent aspects of life and patients experienced depression and anxiety more than others. Tere are several herbal medicines with positive e?ects in these patients. Te aim of this study is to evaluate the e?ects of mixture of Boswellia carterii, Zingiber ofcinale, and Achillea Millefolium on severity of symptoms, anxiety, and depression in IBS patients. Materials and Methods: Tis clinical trial study was done in sixty IBS patients (with mild?to?moderate symptoms) divided into two case and control groups. Patients were assessed at the beginning, 1 month, and 3 months after by IBS?severity scoring system (IBS?SSS) and Hospital Anxiety and Depression Scale. IBS?SSS is used for quality of life evaluation too. Results: Sixty IBS patients (with mild to moderate symptoms) with a mean age of 38.75 ± 11.74 participated that 55.4% of cases and 72.8% of controls were men. Te most prevalent type of IBS was the mixed type of IBS. Te mean score of abdominal pain severity and frequency, bloating score, and depression and anxiety score were decreased in patients administered herbal medication, but changes in these variables in controls were not statistically signifcant. Te changes in quality of life score between cases and controls were signifcant in men (P = 0.01) although it was not signifcant in women. Conclusion: A mixture of B. Carterii, Z. ofcinale, and A. millefolium is e?ective in eliminating IBS symptoms and its related depression and anxiety and using herbal medicine in IBS treatment is suggested.</td></tr></tbody></table> <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10726http://jrms.mui.ac.ir/index.php/jrms/article/download/10726/5566

Journal of Research in Medical Sciences1735-1995221120171203Association between unfavorable lipid profile and glycemic control in patients with type 2 diabetes mellitus1072010720EN20171115Background: Recent studies hypothesize that dyslipidemia can predict glycated hemoglobin (HbA1c) and could be important contributing factor to the pathogenesis of type 2 diabetes mellitus (DM2). Terefore, we aimed to evaluate the in?uence of lipidparameters on long?term glycemic control in DM2. Materials and Methods: A total of 275 sedentary DM2 (mean [±standarddeviation] age 60.6 [±10.0] years) who volunteered toparticipate in this cross?sectional study were enrolled. Anthropometric (bodyweight, body hight, and waist circumference), biochemical parameters (fasting glucose, HbA1c, lipid parameters, creatinine), aswell as blood pressure were obtained. Results: Total cholesterol (odds ratio [OR] =1.30, 95% confdence interval [CI] [1.02–1.66],P = 0.032), triglycerides (OR = 1.34, 95% CI (1.07–1.67), P = 0.010), and low density lipoprotein cholesterol (OR = 1.42, 95%CI [1.10–1.83], P = 0.006) were the independent predictors of higher HBA1c, and as they increased by 1 mmol/L each, probabilitiesof higher HBA1c increased by 30%, 34%, and 42%, respectively. Low level of high?density lipoprotein cholesterol (HDL?c) was foundto be the independent predictor of higher HBA1c (OR = 0.44, 95% CI [0.20–0.67], P = 0.039), and increase in HDL?c by 1 mmol/L,reduced the probability of higher HBA1c by 56%. Conclusion: Unfavorable lipid profle can predict HbA1c level in DM2 patients.Early diagnosis of dyslipidemia, as well as its monitoring and maintaining good lipids control can be used as a preventive measurefor optimal long?term glycemic control. <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10720http://jrms.mui.ac.ir/index.php/jrms/article/download/10720/5567

Journal of Research in Medical Sciences1735-1995221120171203The relationship between fruit and vegetable intake with gastroesophageal reflux disease in Iranian adults1071910719EN20171115<table class="NormalTable"><tbody><tr><td width="550">Background: Findings from studies that investigated the relationship between fruit and vegetable intake with gastroesophageal re?ux disease (GERD) were inconsistent. We aimed to assess the relationship between fruit and vegetable consumption and GERD among a large group of Iranian adults. Materials and Methods: In this cross?sectional study on 3979 adults, a validated food frequency questionnaire was used to assess usual dietary intakes including fruits and vegetables. Te presence of heartburn sometimes or more during the past 3 months were considered as having GERD. Results: Te prevalence of GERD among study population was 23.9%. After adjustment for potential confounding factors, those with the highest consumption of fruits had 25% lower risk for GERD, in comparison to those with the lowest intake (odds ratio [OR] = 0.75, 95% confdence interval [CI]: 0.59–0.97). Vegetable intake was not signifcantly related to the risk of GERD in crude or multivariable?adjusted models. However, participants with the highest intake of fruits and vegetables had 33% lower risk of GERD (OR = 0.67, 95% CI: 0.51–0.88), after adjustment for confounders. Women with the highest fruit and vegetable intake had 36% lower risk for GERD (OR = 0.64, 95% CI: 0.45–0.91). Overweight/obese participants in the last tertile of fruit consumption had 42% lower risk for GERD, in comparison to the frst category (OR = 0.58, 95% CI: 0.42–0.83). Furthermore, participants with body mass index higher than 25 kg/m2 and higher intake of fruits and vegetables had 53% lower risk for GERD (OR = 0.47, 95% CI: 0.32?0.69). Conclusion: We found inverse associations between fruit intake as well as fruit and vegetable intake and risk of GERD among Iranian adults. </td></tr></tbody></table> <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10719http://jrms.mui.ac.ir/index.php/jrms/article/download/10719/5568

Journal of Research in Medical Sciences1735-1995221120171203Effect of Nepeta bracteata Benth. on allergic rhinitis symptoms: A randomized double-blind clinical trial1072110721EN20171115Context: Allergic rhinitis (AR) is one of the health problems in the world. It is necessary to develop new treatment procedure for control of this disease. Aims: Te aim of this study was to assess the effect of Zofa (Nepeta bracteata Benth) on AR patients. Settings and Design: ???. Materials and Methods: In this double-blind randomized clinical trial study, 71 patients (37 patients in treatment and 34 in placebo group) participated. In treatment group, N. bracteata syrup (NBS) was used for 4 weeks as three times a day. Te efficacy of the drug regarding AR symptoms (rhinorrhea, sneezing, nasal obstruction, itchy nose, and ocular symptoms) were evaluated through a visual analog scale (VAS) by 0–10 before administration and at the end of the whole treatment period. Statistical Analysis Used: Te collected information was entered in the SPSS software (version 18) and was analyzed using the Fisher’s exact test, Chi-square test, independent sample t-test, and paired sample test. Results: Te improvement of AR symptoms in the group receiving NBS was significantly higher compared to control group (4.73 ± 1.84 vs. 0.38 ± 2.06; P < 0.0001). Furthermore, the mean of total VAS before and after the treatment (in case group) was 7.10 ± 1.92 and 2.37 ± 1.76, respectively (P < 0.001). Conclusion: Te results of this study indicate that N. bracteata has significant effects on improving the symptoms of AR. Hence, it can be a good alternative to AR symptoms relief. <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10721http://jrms.mui.ac.ir/index.php/jrms/article/download/10721/5569

Journal of Research in Medical Sciences1735-1995221120171203Epidemiology of Q fever in Iran: A systematic review and meta?analysis for estimating serological and molecular prevalence1072210722EN20171115Background: Q fever is endemic in Iran, thus, we conducted a systematic review and meta?analysis on epidemiology of Coxiella <table class="NormalTable"><tbody><tr><td width="550">burnetii among humans and animals in Iran. Materials and Methods: A systematic search was performed to identify all articles reporting C. burnetii prevalence in Iranian humans or animals, published from January 2000 to January 2015. Data from articles were extracted, and a pooled estimate of prevalence with corresponding 95% confdence interval (CI) was calculated using random e?ect method. Results: In this review, 27 papers were identifed. Te pooled seroprevalence of Q fever in animals was 27% (CI 95%: 23%–32%). Te prevalence was 33% (CI 95%: 22%–45%) in goats, 27% (CI 95%: 21%–32%) in sheep, and 17% (CI 95%: 5%–28%) in cattle. Te bacterial DNA was detected in 5% (95% CI: 3%–9%) of milk samples, and it was higher in cattle (10%; 95% CI: 6%–16%) than sheep (2%; 95% CI: 0–7%) and goats (4%; 95% CI: 0–12%). Conclusions: C. burnetii DNA or its antibody has been frequently detected among ruminants. Since these animals can transmit the infection to humans, Q fever could be a potential health problem in Iran. </td></tr></tbody></table> <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10722http://jrms.mui.ac.ir/index.php/jrms/article/download/10722/5573

Journal of Research in Medical Sciences1735-1995221120171203Prevalence of hepatitis C infection in Iranian hemodialysis patients: An updated systematic review and meta-analysis1071710717EN20171115<table class="NormalTable"><tbody><tr><td width="550">Background: Hepatitis C virus (HCV) is a major cause of liver disease and a potential cause of substantial morbidity and mortality. Tis study aims to provide a comprehensive evidence on HCV Infection in Iranian hemodialysis (HD) patients we conducted a systematic review. Materials and Methods: In this systematic review and meta-analysis, through a comprehensive search of literature until January of 2016, we estimated the pooled prevalence of hepatitis C infection in Iranian HD patients. Using Medical Subject Headings terms, Emtree, and related equal Persian key words for Iranian databases and also international databases of PubMed and NLM Gateway (for MEDLINE), and SCOPUS. Interest outcome of HCV infection prevalence was confirmed based on positive hepatitis B surface antigen of blood samples. Random effect meta-analysis was used to estimate pooled prevalence of HCV infection in Iranian HD patients, date and language, HD patients, in adult HD patients, Institute of Scientific Information, Iran-doc, irrespective of age, living in Iran. Searches run through main domestic databanks of Iran-Medex, renal transplantation, Scientific Information Database, the relevant literature-searched concentrating on HCV infection. Results: Trough searching steps, 305 publications were found from them following the excluding duplicates and overlapping studies 54 studies relevant to HCV prevalence in Iranian HD zcxw patients, with number of 23921 participants, remained in our analyses. Te overall results of test of heterogeneity demonstrate sever heterogeneity between reported prevalence (I2 = 96.62%, Chi-square = 1566, P < 0.001). Due to sever heterogeneity results of random effect meta-analysis showed that the estimated pooled prevalence was 11% (95% confidence interval [CI] =10%–13%). Te pooled prevalence base on polymerase-chain reaction, recombinant immunoblot assay, and enzyme-Linked Immunosorbant Antibody method were 11% (95% CI = 6%–15%), 9% (95% CI = 5–13) and 12% (95% CI = 10–14), respectively. In line with previous studies, the present finding shows the significant variation in the rate of HCV in dialysis units among the regions in Iran. Conclusions: Present paper is the comprehensive updated systematic review on HCV prevalence in the Iranian HD patients. Our findings provide the reliable evidence for promotion of policies and interventional programs. </td></tr></tbody></table><br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10717http://jrms.mui.ac.ir/index.php/jrms/article/download/10717/5571

Journal of Research in Medical Sciences1735-1995221120171203An atypical presentation of pulmonary sequestration1071810718EN20171115Pulmonary sequestration (PS) is a rare congenital malformation of the lower respiratory tract and is commonly complicated by recurrent infections and presents with respiratory failure.[1] We report an atypical clinical presentation of postprandial abdominal pain and cramps in a patient with intralobar PS. <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10718http://jrms.mui.ac.ir/index.php/jrms/article/download/10718/5572

Journal of Research in Medical Sciences1735-1995221120171203Can cool dialysate alleviate restless leg syndrome in hemodialysis patients?1072310723EN20171115-http://jrms.mui.ac.ir/index.php/jrms/article/view/10723http://jrms.mui.ac.ir/index.php/jrms/article/download/10723/5570

Journal of Research in Medical Sciences1735-1995221120171203Accelerated rigor mortis: A case letter1072410724EN20171115-http://jrms.mui.ac.ir/index.php/jrms/article/view/10724http://jrms.mui.ac.ir/index.php/jrms/article/download/10724/5574