Journal of Research in Medical Sciences1735-1995181220131217A brief overview of methamphetamine use treatment in Iran: Intervention and practice97849784EN20131216---http://jrms.mui.ac.ir/index.php/jrms/article/view/9784http://jrms.mui.ac.ir/index.php/jrms/article/download/9784/4046Journal of Research in Medical Sciences1735-1995181220131217Role of cyclin D1 in breast carcinoma97859785ENDepartments of Pathology, School of Medicine, Isfahan University of Medical Sciences,Isfahan,IranDepartments of Pathology, School of Medicine, Isfahan University of Medical Sciences,Isfahan,Iran20131216---http://jrms.mui.ac.ir/index.php/jrms/article/view/9785http://jrms.mui.ac.ir/index.php/jrms/article/download/9785/4058Journal of Research in Medical Sciences1735-1995181220131217Comparing the cancer in Ninawa during three periods (1980–1990, 1991–2000, 2001–2010) using poisson regression97869786ENSchool of Mathematics and Statistics, Huazhong University of Science and Technology, Wuhan, Hubei, China20131216Background: Iraq fought three wars in three consecutive decades, Iran-Iraq war (1980-1988), Persian Gulf War in 1991, and the Iraq’s war in 2003. In the nineties of the last century and up to the present time, there have been anecdotal reports of increase in cancer in Ninawa as in all provinces of Iraq, possibly as a result of exposure to depleted uranium used by American troops in the last two wars.This paper deals with cancer incidence in Ninawa, the most importance province in Iraq, where many of her sons were soldiers in the Iraqi army, and they have participated in the wars. Materials and Methods: The data was derived from the Directorate of Health in Ninawa. The data was divided into three sub periods: 1980-1990, 1991-2000, and 2001-2010. The analyses are performed using
Poisson regressions. The response variable is the cancer incidence number. Cancer cases, age, sex, and years were considered as the explanatory variables. The logarithm of the population of Ninawa is used as an offset. The aim of this paper is to model the cancer
incidence data and estimate the cancer incidence rate ratio (IRR) to illustrate the changes that have occurred of incidence cancer in Ninawa in these three periods. Results: There is evidence of a reduction in the cancer IRR in Ninawa in the third period as well as in
the second period. Our analyses found that breast cancer remained the first common cancer; while the lung, trachea, and bronchus the second in spite of decreasing as dramatically. Modest increases in incidence of prostate, penis, and other male genitals for the duration of the study period and stability in incidence of colon in the second and third periods. Modest increases in incidence of placenta and metastatic tumors, while the highest increase was in leukemia in the third period relates to the second period but not to the first period. The cancer IRR in men was decreased from more than 33% than those of females in the first period, more than 39% in the second period, and regressed to 9.56% in the third period. Conclusion: Our paper confirms the media reports that there
are increases in the number of cancer cases, but when it analyzed statistically with population growth in the Ninawa province, there are decreases in incidence rates in most cancer types.
Key words: Cancer, incidence rate ratio, Ninawa, Poisson regressionhttp://jrms.mui.ac.ir/index.php/jrms/article/view/9786http://jrms.mui.ac.ir/index.php/jrms/article/download/9786/4059Journal of Research in Medical Sciences1735-1995181220131217Life expectancy after HIV diagnosis based on data from the counseling center for behavioral diseases97879787ENDepartment of Epidemiology and Biostatistics, Isfahan University of Medical Sciences, Isfahan, Iran.20131216Background: Predicting life expectancy is an important component of public health, in that, it may affect policy making in fields
such as social security and medical care., To estimate the life expectancy and the average years of life lost (AYLL) of the human
immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS)-infected population, compared with that of the general
population, and also to assess the impact of the CD4 count, risk factors of transmission, marital status, and employment status on
life expectancy. Material and Methods: This study is a population-based cohort study. The sample consisted of HIV/AIDS-infected
patients receiving care from 2001-2011. The patients were all adults (20-64 years) who were recruited from the Counseling Center
of Behavioral Diseases. Life expectancy was measured based on an abridged life table, according to age-specific mortality rates and
average years of life lost (AYLL) during the study period. Results: Forty-three of the 205 eligible patients died during 853 personyears
follow-up. Compared to the general population, the life expectancy for patients with HIV infection at age 20 is about 36 years
less. We have found that out a total of 1597 years of life lost during 2001-2011, compared to an overall AYLL for all HIV/AIDS, the deaths had occurred 36 years earlier than the life expectancy. Conclusion: Life expectancy in HIV/AIDS-infected patients is about
38 years less than that of the general population at the exact age of 20. The deaths caused by HIV/AIDS occurred about 36 years before what was expected in the general population at ages 20-64, and many of these years of life lost could be saved if the health
care system was implemented against the risk factors of HIV/AIDS.
Key words: Acquired Immunodeficiency Syndrome (AIDS), HIV, life expectancy, mortalityhttp://jrms.mui.ac.ir/index.php/jrms/article/view/9787http://jrms.mui.ac.ir/index.php/jrms/article/download/9787/4060Journal of Research in Medical Sciences1735-1995181220131217Absent CD56 expression in papillary thyroid carcinoma: A finding of potential diagnostic value in problematic cases of thyroid pathology97889788ENDepartment of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran20131216Background: There are inter-observer disagreements between papillary thyroid carcinoma (PTC) with other follicular lesions
of thyroid in aspect of diagnosis. CD56 is present on follicular epithelial cells of the normal thyroid. We evaluated the diagnostic
value of CD56 expression in PTC, follicular thyroid lesions, and follicular thyroid neoplasms. Materials and Methods: Seventythree cases diagnosed as follicular lesions and 73 cases diagnosed as PTC were stained with CD56 marker. A positive membranousimmunostaining in more than 10% of the neoplastic cells qualified the case as “positive (+)†for CD56. Results: CD56 expression was seen in 70 samples of non-papillary carcinoma lesion (95.8%) versus one case of PTC (1.3%) (P < 0.001, Chi-square). Therefore,CD56 was 98.6% sensitive and 95.8% specific in distinguishing PTC from other follicular thyroid lesions. Conclusion: CD56 is both a sensitive and specific marker for differentiating PTC from other follicular lesions of thyroid singly but it may be better to use a combination of markers for clinical evaluation of patients.
Key words: CD56, papillary thyroid carcinoma, thyroid neoplasms, thyroid nodulehttp://jrms.mui.ac.ir/index.php/jrms/article/view/9788http://jrms.mui.ac.ir/index.php/jrms/article/download/9788/4047Journal of Research in Medical Sciences1735-1995181220131217Comparing results of clinical versus ultrasonographic examination in developmental dysplasia of hip97899789ENReasercher in Vice Chancellery for Research, Isfahan University of Medical Sciences , Isfahan, Iran20131216Background: Developmental dysplasia of hip (DDH) is one of the congenital anomalies in newborns that if not diagnosed and treated on time can lead to a severe disability. Although clinical examination is a very useful way for screening, but in some patients, a confirmatory diagnostic method such as ultrasonography is needed. The aim of the present study is to compare the sensitivity and specificity of clinical examination and ultrasonography in early detecting of DDH. Materials and Methods: A total of 5800 of newborns were examined by orthopedic surgeon as a screening method. The newborns with risk factors or suspicious on clinical examination were introduced to repeat clinical and ultrasonographic examination of hip. The results were collected and recorded by a check list and then the sensitivity and specificity of clinical examination were calculated. Results: Of 5701 newborns (11402 hips) who were studied by two methods of clinical examination and ultrasonography (by Graf method), the overall incidence of DDH was 29 per 1000. Only 94 hips (13.5%) of 694 disordered ones according to clinical examination were involved on ultrasonographic evaluation. A total of 240 hips of 334 (72%) involved hips according to ultrasonography (Graf type IIb or more) were diagnosed normal on clinical examination, considering ultrasonography as a gold standard method of evaluating DDH, the sensitivity and specificity of clinical examination were calculated 28.1% and 94.5%, respectively. Conclusion: According to the present study, ultrasonogeraphic examination has a high valuable in screening of DDH and the clinical examination done by an experienced orthopedic surgeon has an acceptable value in primary screening of DDH in developing countries for detecting of healthy neonates, but if the newborn has a risk factor or is suspicious on clinical examination, it will be necessary to get assistance from ultrasonography by an experienced sonographer.
Key words: Developmental dysplasia of hip (DDH), instability, dislocation, subluxation, ultrasonographyhttp://jrms.mui.ac.ir/index.php/jrms/article/view/9789http://jrms.mui.ac.ir/index.php/jrms/article/download/9789/4061Journal of Research in Medical Sciences1735-1995181220131217Resistance pattern of Helicobacter pylori strains to clarithromycin, metronidazole, and amoxicillin in Isfahan, Iran97909790ENDepartment of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan , Iran20131216Background: Helicobacter pylori (H. pylori) resistance to antibiotics has become a global problem and is an important factor in determining the outcome of treatment of infected patients. The purpose of this study was to determine the H. pylori resistance to
clarithromycin, metronidazole, and amoxicillin in gastrointestinal disorders patients. Materials and Methods: In this study, a total
of 260 gastric antrum biopsy specimens were collected from patients with gastrointestinal disorders who referred to Endoscopy Section of the Isfahan Hospitals. The E-test and Modified Disk Diffusion Method (MDDM) were used to verify the prevalence of antibiotic resistance in 78 H. pylori isolates to the clarithromycin, metronidazole, and amoxicillin. Results: H. pylori resistance to clarithromycin, metronidazole, and amoxicillin were 15.3, 55.1, and 6.4%, respectively. In this study¸ we had one multidrug resistance (MDR) isolates from patient with gastritis and peptic ulcer disease. Conclusion: Information on antibiotic susceptibility profile plays an important role in empiric antibiotic treatment and management of refractive cases. According to the results obtained in this study, H. pylori resistance to clarithromycin and metronidazole was relatively high. MDR strains are emerging and will have an effect on the combination therapy.
Keywords: Amoxicillin, clarithromycin, Helicobacter pylori, metronidazolehttp://jrms.mui.ac.ir/index.php/jrms/article/view/9790http://jrms.mui.ac.ir/index.php/jrms/article/download/9790/4048Journal of Research in Medical Sciences1735-1995181220131217Proton magnetic resonance spectroscopy and cognitive impairment in patients with ischemic white matter lesions97919791ENDepartment of Neurology, China-Japan Union Hospital, Ji Lin University, Changchun, China20131216Background: The purpose of this study is to investigate the relationship between the cognitive impairment and NAA/Cr and Cho/Cr ratios in the proton magnetic resonance spectroscopy (1HMRS), and to assess the importance of 1HMRS in the early diagnosis of
cognitive impairment in patients with ischemic white matter lesions (WMLs). Materials and Methods: A total of 45 patients (23males and 22 females) with the ischemic WML were divided into mild WML group (n = 15), moderate WML group (n = 15), and severe WML group (n = 15). A total of 15 healthy controls (8 males and 7 females) with no WML on magnetic resonance imaging were included. 1HMRS focusing on the frontal lobe white matter around the anterior horn of the lateral ventricle and Montreal Cognitive Assessment (MoCA) were conducted. Results: Patients with more severe WML had lower MoCA scores. The NAA/Cr
ratio in 1HMRS was reduced in all the patients and was strongly correlated with the total MoCA scores (r = 0.845, P < 0.001). The Cho/Cr ratio in 1HMRS was increased in mild and moderate patients, was negatively correlated with the total MoCA scores (r =
0.907, P < 0.001). The Cho/Cr ratio was reduced in the severe patients and was positively correlated with the total MoCA scores(r = 0.937, P < 0.001). In addition, NAA/Cr and Cho/Cr ratios in 1HMRS were changed in patients with the mild WML whose total MoCA scores were similar to the controls. Conclusion: Our results suggest that NAA/Cr and Cho/Cr ratios in 1HMRS are useful indicators for early diagnosis of ischemic WML and cognitive impairment in patients with ischemic WML.
Keywords: 1HMRS, Cho/Cr ratio, cognitive impairment, ischemic white matter, montreal cognitive assessment, NAA/Cr ratio,
white matter lesionshttp://jrms.mui.ac.ir/index.php/jrms/article/view/9791http://jrms.mui.ac.ir/index.php/jrms/article/download/9791/4049Journal of Research in Medical Sciences1735-1995181220131217The role of molds in the relation between indoor environment and atopy in asthma patients97939793ENDepartment of Pulmonary Medicine, Gaziosmanpasa University, Tokat 60100, Turkey20131216Background: The effect of mold fungi to allergic sensitization is not well-known. We aimed to evaluate the role of molds in the relation between indoor environment and atopy in asthmatics. Materials and Methods:The air samples obtained from 66 stable
asthmaticsand 35 control subject’shouses were sprayed into Sabouraud dextrose agar. Allergy skin testing were performed both groups. The temperature and humidity of each house were measured. Results:The incidence of atopy was similar in cases (59.1%) and controls (51.4%). The average amount of mold was 35.9 CFU/m3 and 34.3 CFU/m3, respectively. The number of household residents was positively correlated with the amount of molds. There was no difference in the amount of mold with respect to dosage of inhaler
corticosteroids as well as symptom levels in asthmatics. The most frequently encountered allergens were Dermatophagoides farinae/Dermatophagoides pteronyssinus, grass and weeds and molds. Spending childhood in a village was more common among atopics.
Conclusion: Living environment during the childhood might affect atopy and asthma. Based on the identification of molds as the second most frequent allergen after mites in our study population, assessment of mold sensitization as well as in forming patients about ways to avoid them seem likely to contribute to the effective management of uncontrolled asthma.
Key words: Air pollution, asthma, indoor environment, moldhttp://jrms.mui.ac.ir/index.php/jrms/article/view/9793http://jrms.mui.ac.ir/index.php/jrms/article/download/9793/4067Journal of Research in Medical Sciences1735-1995181220131217Relation of Air pollution with Epidemiology of Respiratory Diseases in Isfahan, Iran from 2005 to 200997949794ENDepartment of Geography, Isfahan University, Isfahan, Iran20131216Background: National Institute of Environmental Health Sciences (NIEHS) scientists shows that long-term exposure to air pollutants increases the risk of respiratory diseases such as allergies, asthma, chronic obstructive pulmonary disease, and lung cancer. Children and the elderly are particularly vulnerable to the health effects of ozone, fine particles, and other airborne toxicants. Air pollutionn factors are considered as one of the underlying causes of respiratory diseases. This study aimed to determine the association of
respiratory diseases documented in medical records and air pollution (Map distribution) of accumulation in Isfahan province, Iran.By plotting the prevalence and spatial distribution maps, important differences from different points can be observed. Materials
and Methods: The geographic information system (GIS), pollutant standards index (PSI) measurements, and remote Sensing (RS) technology were used after entering data in the mapping information table; spatial distribution was mapped and distribution of
Geographical Epidemiology of Respiratory Diseases in Isfahan province (Iran) was determined in this case study from 2005 to 2009.Results: Space with tracing the distribution of respiratory diseases was scattered based on the distribution of air pollution in the
points is an important part of this type of diseases in Isfahan province where air pollution was more abundant. Conclusion: The findings of this study emphasis on the importance of preventing the exposure to air pollution, and to control air pollution product
industries, to improve work environmental health, and to increase the health professionals and public knowledge in this regard.
Key words: Air pollution, Iran, Isfahan province, respiratory diseases, spatial distributionhttp://jrms.mui.ac.ir/index.php/jrms/article/view/9794http://jrms.mui.ac.ir/index.php/jrms/article/download/9794/4050Journal of Research in Medical Sciences1735-1995181220131217The effects of green tea consumption on metabolic and anthropometric indices in patients with Type 2 diabetes97959795ENDepartment of Nutrition, School of Public Health, Iran University of Medical Sciences, Alvand Avenue, Arjantin Square, Tehran, Iran20131216Background: This study aims at investigating the possible effects of different daily doses of green tea (GT) intake for eight weeks on certain anthropometric, metabolic, and oxidative stress biomarkers of diabetic patients. Materials and Methods: This randomized clinical
trial included 63 patients with type 2 diabetes (30 males and 33 females). After a two-week run-in period without green tea, they were randomly assigned into one of the three groups, with a different daily intake of green tea; four cups of green tea per day (n = 24),two cups of green tea per day (n = 25), and the control group (n = 14) with no green tea intake for two months. At baseline and after the intervention, blood tests, dietary, and anthropometric variables were assessed. The patients were instructed to maintain their usual dietary intake and normal physical activity. Results: Consumption of four cups of GT per day caused a significant decrease in body weight (73.2 to 71.9) (P < 0.001), body mass index (27.4 to 26.9) (P < 0.001), waist circumference (95.8 to 91.5) (P < 0.001), and
systolic blood pressure (126.2 to 118.6) (P < 0.05) in this group. No significant change was seen in the other groups and between group comparisons. The metabolic and oxidative stress parameters did not show any significant differences within and between groups.
Conclusion: Drinking four cups of green tea led to a significant reduction in weight and systolic blood pressure.
Key words: Anthropometric indices, green tea, metabolic indices, Type 2 diabeteshttp://jrms.mui.ac.ir/index.php/jrms/article/view/9795http://jrms.mui.ac.ir/index.php/jrms/article/download/9795/4066Journal of Research in Medical Sciences1735-1995181220131217Floating knee injuries: Results of treatment and outcomes97969796ENGeneral Physician, Department of Orthopedic Surgery, Medical School,Isfahan University of Medical Sciences, Isfahan, Iran.20131216Background: Floating knee, referred to as ipsilateral fractures of the femur and tibia, is usually associated with several complications and mortality. This study was designed to present our experience with treatment of this injury throughout; age, sex, mechanism
of injury, associated injuries, method and results of treatment, and complications of floating knee are discussed. Materials and Methods: This retrospective study was performed between January 2006 and December 2011. All patients with floating knee injuries
who were admitted to the referral educational hospitals were included. The information about the 238 cases of floating knee injuries were gathered through the 254,620 trauma files and after excluding 18 patients who died within 6 months, the remaining files were
studied and the target information was recorded. Results: The most frequent age group was 20-29 years (44.5%). The floating knee injuries were more common in males (85.5%). Type (D) according to “the classification of Letts and Vincent†was observed in 38.9% cases. The most frequent mechanism of injury was car to motorcycles accidents (48.2%). The most common associated injury was pelvic fractures (86.8%). Open reduction and internal fixation was the common type of treatment (70%). The most common early and
late complications were knee hemarthrosis in 31 cases (14%) and knee osteoarthritis in 30 cases (13.6%), respectively. Death during the 5 years follow up was due to circulatory disruption, followed by deep vein thrombosis (61%). There was a significant relation
between the age and outcomes as it worsens with age (P-value < 0.05). Conclusion: This study revealed that the complication rate associated with floating knee injuries remained high, regardless of the used treatment regimen and surgeons should focus on reducing complications while treating it.
Key words: Femoral fracture, floating knee injury, tibia fracturehttp://jrms.mui.ac.ir/index.php/jrms/article/view/9796http://jrms.mui.ac.ir/index.php/jrms/article/download/9796/4065Journal of Research in Medical Sciences1735-1995181220131217Double tibial osteotomy for bow leg patients: A case series97929792ENDepartment of orthopedics, Isfahan Medical University, Isfahan, Iran20131216Background: High tibia osteotomy (HTO) is a common surgical operation for correction of genu varum deformity. In some patients,there are concurrent tibia vara and genu varum (bow leg). This study aimed to consider the possibility of better correction of bow leg
deformity after double level tibial osteotomy (DLTO). Materials and Methods: A case series of 10 patients of genu varum in addition to tibia vara (bow leg) deformity who were referred to orthopedic ward of an academic hospital of Isfahan- Iran during 2009–2011
were included in the study. The mean age was 17.3 ± 3.1 years and all of them underwent DLTO. The results of treatment have been assessed based on clinical and radiological parameters before and after surgery. Results: The mean pre- and post operative values for
Tibia-Femoral Angle, Medial Proximal of Tibia Angle (MPTA), and Lateral Distal of Tibia Angle (LDTA) were 18.13 ± 3.05° vs. 3.93± 0.66°, 79.13 ± 3.4° v s. 89.7 ± 1.8° and 96.40 ± 1.8° vs. 88.73 ± 3.0° respectively (P < 0.05). Improvement of all radiological parameters
was meaningful. Seventy three percent of patients had normal mechanical axis of limb after surgery. The remaining cases had varus deformity in distal femur that was corrected by valgus supracondylar osteotomy in an additional operation. Limited range of motion(ROM) near knee and ankle was not observed. Conclusion: DLTO correct bow leg deformity in the point of alignment of limb and paralleling of knee and ankle joint more effectively. This method can be used in metabolic and congenital bow leg which deformities are present in throughout of the lower limb. We described this technique for the first time.
Key words: Bow leg, double tibial osteotomy, genu varum, limb alignment, osteotomy, tibiahttp://jrms.mui.ac.ir/index.php/jrms/article/view/9792http://jrms.mui.ac.ir/index.php/jrms/article/download/9792/4062Journal of Research in Medical Sciences1735-1995181220131217Endoscopic gastrostomy, nasojejunal and oral feeding comparison in aspiration pneumonia patients97979797ENDepartment of General Surgery, Fatih Sultan Mehmet Research and Training Hospital, Istanbul, Turkey20131216Background: Aspiration pneumonia is a potentially preventable illness requiring attention to small details of patient care. The type, management, and care of feeding should be carried out properly. Materials andMethods: This is a prospective clinical study
of enteral feeding on patients admitted to hospital with aspiration pneumonia. The known enteral nutritional methods, advantages,and disadvantages were told to the patient or proxy. If they didn’t accept Percutaneous endoscopic gastrostomy (PEG), nasojejunal tube (NJT) was advised. If they denied all of the procedures, oral feeding education was given. A total of 94 patients were enrolled to the study, 29 of them accepted PEG, 42 preferred NJT, and 23 preferred oral route. Results: A total of 94 patients with a mean age of 77.84, standard deviation 10.784; 95% confidence interval (CI) 75.63-80.03 were enrolled to the study of which 27 (28.7%) patients had a history of aspiration pneumonia. Oral feeding was prominently preferred for patients nursed by a relative (15; 65.2% of Oral feeding group and 16% of total) or a caregiver (7; 30.4% of Oral feeding group and 7.4% of total) while only 1 (4.3% of Oral feeding
group and 1.1% of total) with a health-care worker (P = 0.001). Overall re-aspiration rates at the 6th month were 58%, 78%, 91% in EG,NJT, oral groups, respectively. Sixth months’ survival rates of the different feeding groups were not significantly divergent from each other. History of aspiration was also found to be a significant contributor of mortality. Conclusion: In aspiration pneumonia patients’ long-term survival rates of the different feeding groups were not significantly divergent from each other.
Key words: Aspiration pneumonia, emergency department, enteral feeding, mid arm circumference, nasojejunal tube, nutrition,oral feeding, percutaneous endoscopic gastrostomyhttp://jrms.mui.ac.ir/index.php/jrms/article/view/9797http://jrms.mui.ac.ir/index.php/jrms/article/download/9797/4063Journal of Research in Medical Sciences1735-1995181220131217The association between natural disasters and violence:A systematic review of the literature and a call for more epidemiological studies97989798ENDepartmentofSocialMedicine,OccupationalEnvironmentalResearchCenter,RafsanjanMedicalSchool,RafsanjanUniversityofMedicalSciences,Rafsanjan,Iran20131216The links between disasters and violence either self-directed or interpersonal are now more recognized. Nevertheless, the amount of research is limited. This article discusses the underlying association of disasters and violence and it also outlines a systematic review
of the literature from 1976 to 2011. Finally, it concludes and recommends particular approaches for further epidemiological research.
Key words: Epidemiological studies, natural disasters, interpersonal violence, self-directed violencehttp://jrms.mui.ac.ir/index.php/jrms/article/view/9798http://jrms.mui.ac.ir/index.php/jrms/article/download/9798/4057Journal of Research in Medical Sciences1735-1995181220131217Flecainide associated torsade de pointes: A potential case of reverse use dependence97999799ENDepartment of Cardiology, University of Arkansas for Medical Sciences, United States20131217Flecainide has been known to cause torsades de pointes (TdP) in patients with structural heart disease and its mechanism has been attributed to use-dependency. We present a patient with flecainide-induced TdP in the absence of any other precipitating factors.This case highlights potential reverse use dependence associated with flecainide resulting in TdP.
Key words: Arrhythmias, clinical electrophysiology, drugs, electrophysiology, receptor pharmacologyhttp://jrms.mui.ac.ir/index.php/jrms/article/view/9799http://jrms.mui.ac.ir/index.php/jrms/article/download/9799/4055Journal of Research in Medical Sciences1735-1995181220131217Locoregional invasion of buccal squamous cell carcinoma into the maxillary, palatal and mandibular bones,a case report98009800ENPostgraduate Student of Oral and Maxillofacial Radiology, Faculty of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran20131217Squamous cell carcinoma (SCC) of the buccal mucosa accounts for 23% to 37% of all intraoral cancers, the prognosis is generally poor. we reported a case of Local invasion of buccal squamous cell carcinoma. A 32-year-old man referred to the clinic with a chief complaint of swelling in the right cheek region that initiated from 6 months ago and rapidly grow from one month ago. History of the patient revealed that he was undergoing a surgery for buccal Squamous cell carcinoma (SCC) lesion 2 years ago. Computed tomography (CT) and Magnetic resonance(MRI) images showed a heterogenous mass in the right maxillary, palate and mandibular regions that was histopathologically diagnosed as recurrence with locoregional invasion of SCC.
Key words: Buccal mucosa, maxilla, squamous cell carcinomahttp://jrms.mui.ac.ir/index.php/jrms/article/view/9800http://jrms.mui.ac.ir/index.php/jrms/article/download/9800/4056Journal of Research in Medical Sciences1735-1995181220131217Large retroperitoneal paraganglioma concurrent with periampullary adenocarcinoma98019801ENDepartment of Pathology, Poursina Research Institution, Poursina Research Institution, Isfahan, Iran.20131217Paragangliomas are tumors that originate from extra-adrenal medullary neural crest derivatives. They are rarely located in retroperitoneal space. These tumors are often discovered incidentally during imaging studies performed for other reasons.Periampullary cancers include adenocarcinomas arising from the pancreas, ampulla of Vater, duodenum or distal common bile duct.
The exact site of origin of periampullary tumors is often difficult to ascertain pre-operatively. We report the case of a patient who had a retroperitoneal non-functional paraganglioma, concurrent with periampullary adenocarcinoma. An 81-year-old woman was admitted
with progressive abdominal fullness. There was an upper paramedian, left sided, large, palpable mass on the physical examination.Laboratory investigations showed an increase in liver enzyme levels. On abdominal computed tomography the patient found to have a large retroperitoneal mass and dilation in biliary tract, which was confirmed by magnetic resonance cholangiopancreatography. She had a tumoral papi in Endoscopic Retrograde cholangiopancreatography. Which biopsy revealed adenocarcinoma. She underwent surgery for excision of abdominal mass and pancreaticoduodenectomy. And pathologic study showed paraganglioma. This is the first ever reported case of concurrent paraganglioma and periampullary adenocarcinoma.
Key words: Paraganglioma, periampullary carcinoma, retroperitoneal masshttp://jrms.mui.ac.ir/index.php/jrms/article/view/9801http://jrms.mui.ac.ir/index.php/jrms/article/download/9801/4054Journal of Research in Medical Sciences1735-1995181220131217Ischemic colitis resulting from colonoscopy in a patient with irritable bowel syndrome98029802ENWuxi People’s Hospital Affiliated to Nanjing Medical University, Wuxi City, Jiangsu Province, China20131217---http://jrms.mui.ac.ir/index.php/jrms/article/view/9802Journal of Research in Medical Sciences1735-1995181220131217Obesity predictors in people with chronic spinal cord injury: Common mistake98039803ENDepartment of Clinical Epidemiology, Safety Promotion and Injury Prevention Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran20131217---http://jrms.mui.ac.ir/index.php/jrms/article/view/9803Journal of Research in Medical Sciences1735-1995181220131217Comment on: A model for prediction of cisplatin induced nephrotoxicity by kidney weight in experimental rats98049804ENDepartment of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran20131217--http://jrms.mui.ac.ir/index.php/jrms/article/view/9804http://jrms.mui.ac.ir/index.php/jrms/article/download/9804/4052