Journal of Research in Medical Sciences1735-199514420090511An image processing technique for diagnosis of Alzheimer's disease205209ENIran Univ. Med. Sci.Razi Institute Drug Research, Department of Pharmacology, IranRazi Institute Drug Research, Department of Pharmacology, Iran200810222009030220090126<ul><li><strong>BACKGROUND</strong>: Patients with Alzheimer's disease (AD) reportedly hibit hypersensitivity to much diluted tropicam solution (0.005%), a M4 muscarinic receptor antagonist. Therefore aocular application of 0.005% tropicamide ma be useful for screening dementia. The aim of this study was to simplify the pupil response test by using a new image analyzing system, which consists of a cheap, simple, and easy to use web-camera and a computer.</li><li><strong>METHODS</strong>: Intraocular tropicamide of 0.005% concentration was administered in 3 groups: Alzheimer's disease patients (n = 8, average age = 76 ± 5), non-Alzheimer's disease elderly (n = 6, average age = 65 ± 7), and young subjects (n = 8, average age = 28 ± 5). Every 5 minutes for 60 minutes, image of the eye's shape were taken, and the diameter of the pupils was measured.</li><li><strong>RESULTS</strong>: The results showed that differences in pupil dilation rate between Alzheimer's disease and non-Alzheimer's disease subjects were statistically significant. ROC analysis showed that after 35 minutes the sensitivity and specificity of the test were 100%.</li><li><strong>CONCLUSIONS</strong>: Based on our results, we concluded that this recording system might be an appropriate and reliable tool for pupil response diagnosis test of Alzheimer's disease.</li><li><strong>KEYWORDS</strong>: Alzheimer’s Disease, Tropicamide, Pupil.</li></ul>http://jrms.mui.ac.ir/index.php/jrms/article/view/2509http://jrms.mui.ac.ir/index.php/jrms/article/download/2509/1632Journal of Research in Medical Sciences1735-199514420090202Fatty acid composition of commercially available Iranian edible oils211215ENDep. of Biology, Faculty of Sciences, Tehran payame noor UniversityCardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, IranCardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran2008111020090202<font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><ul><li><div align="left"><strong>BACKGROUND</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Trans-fatty acids (TFAs), unsaturated fats with at least one double bond in the Trans configuration, are industrially formed in large quantities when vegetable oils are partially hydrogenated. This study was ndertaken to quantify the amounts of the common fatty acids in several commercial oils marketing in Iran.</font></font></div></li><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>METHODS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">The most consumed commercially available brands of vegetable oils were randomly selected from products available in supermarkets. A 10g sample was drawn from each mixed sample and prepared for fatty cid analysis by gas chromatography (GC).</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>RESULTS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Palmitic acid (C16:0) and stearic acid (C18:0) jointly constituted 21% of total fatty acids in partially hydrogenated vegetable oils (PHVOs). More than one third of total fatty acids in Iranian PHVOs were Trans fats. TFAs constituted almost 1% and 3% of total fatty cids in Iranian cooking and frying oils. This study howed higher contents of TFAs in Iranian commercially available hydrogenated vegetable oils. Statistical Package for Social Sciences was used for all statistical analyses.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>CONCLUSIONS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Although several studies reported multiple adverse effects of TFAs on human health, limited nformation is available about total fatty acid composition, particularly TFAs, in Iranian edible oils. Our findings indicated higher content of TFAs in Iranian commercially available PHVOs.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>KEYWORDS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Fatty Acids, Vegetable Oils, Trans Fats.</font></font></div></li></font></font></ul></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/2601http://jrms.mui.ac.ir/index.php/jrms/article/download/2601/1634Journal of Research in Medical Sciences1735-199514420090511Association of catechol-o-methyl transferase gene polymorphism with prostate cancer and benign prostatic hyperplasia217222ENDR.Uromia Medical Science UniversityUromia Medical Science University2008122020090303<font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><ul><li><div align="left"><strong>BACKGROUND</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">A single nucleotide variation within atechol-o-methyl transferase (COMT) gene may alter the COMT enzyme activity level. Polymorphism of Val158Met in the COMT gene has been related to malignancy. In this regard, a study was carried out to find a possible association between the COMT gene polymorphism in patients with sporadic prostate cancer (PCa) and benign prostatic hyperplasia (BPH).</font></font></div></li><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>METHODS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">All types of COMT158 Val/Met polymorphism were carried out using ASO-PCR method in 41 patients with prostate cancer, 193 patients with benign prostatic hyperplasia and 107 healthy male individuals.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>RESULTS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">The results of this study showed that the frequency of low producer allele A at codon 158 of the OMT gene is significantly different in BPH group compared to normal male control group (OR, 95% CI, p value 1.95: 1.46, 2.44, 0.021, respectively). However no significant difference was noticed when the comparison was made between prostate cancer group and normal male control group and also between BPH and PCa groups.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>CONCLUSIONS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Decreased level of catechol-o-methyl transferase gene activity may play a possible role in benign prostatic hyperplasia development but not in prostate cancer. Increased level of COMT gene activity has a protective role against BPH.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>KEYWORDS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Prostate Cancer, Benign Prostatic yperplasia, COMT 158Val/Met Polymorphism.</font></font></div></li></font></font></ul></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/2741http://jrms.mui.ac.ir/index.php/jrms/article/download/2741/1635Journal of Research in Medical Sciences1735-199514420090129Effect of physical training on metabolic responses of pregnant rats submitted to swimming under thermal stress223230ENUniversidade Federal de São Paulo, São Paulo, BrazilUniversidade do Vale do ParaÃba, São José dos Campos, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilLaboratório de Fisiologia e Biocinética, UNIG Campus V, BrazilUniversidade do Vale do ParaÃba, São José dos Campos, BrazilUniversidade Federal de São Paulo, São Paulo, Brazil2008111820090129<font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><ul><li><div align="left"><strong>BACKGROUND</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">The aim of this study is to assess the effect of pre-pregnancy physical training on metabolic responses and its effects on offspring.</font></font></div></li><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>METHODS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Three groups of rats (n = 7 in each group): sedentary pregnant rats (PS), exercised during regnancy (PE) and pregnant rats trained before and during pregnancy (PT) were compared. They were separated nto three subgroups regarding water temperature: 28°C, 35°C or 39°C. Plasma triglycerides and glucose levels, eight gain during pregnancy and rectal temperature pre and post exercise (swim), as well as the offspring size and weight were analysed.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>RESULTS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Rectal temperature post exercise was lower than pre exercise at 28°C and 35°C, and higher at 39°C. eight gain was lower at 39°C for the PT group and at 35°C for the PT and PE groups compared to the PS group. Plasma glucose, at 28°C and 39°C for PS and PE groups, was higher than those obtained at 35°C, while triglycerides ere lower. For trained rats, plasma glucose and triglycerides were similar at all water temperatures. rained rats presented lower triglyceride values at 35°C, and higher triglyceride values at 39°C compared to PS roup. Glucose presented inverse results. None of the groups presented fetal reabsorption. However, in the PS group, the offspring presented lower weight gain at 28°C than at 35°C and 39°C.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>CONCLUSIONS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">These results suggest that pre-pregnancy physical training induces steady values of triglycerides and glucose during exercise at all water temperatures.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>KEYWORDS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Physical Training, Pregnant Rats, Glucose Metabolism, Triglycerides Metabolism, Thermal Stress.</font></font></div></li></font></font></ul></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/2650http://jrms.mui.ac.ir/index.php/jrms/article/download/2650/1521Journal of Research in Medical Sciences1735-199514420090603Hypothalamic-pituitary-gonadal axis responses of the male rats to short and long time alternative magnetic fields (50 Hz) exposure231238EN200809242009050120090114<font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><ul><li><div align="left"><strong>BACKGROUND</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Electromagnetic fields are associated with production, transmission and use of electricity. In this tudy we have investigated the effects of short and long time alternative magnetic fields' (AMF, 50 Hz) exposure on the secretion of hypothalamic-pituitary-gonadal axis in the male rats.</font></font></div></li><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>METHODS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Forty eight Wistar male rats, same range of age and weight were divided into four groups and each group<li><div align="left">contained 12 rats. After one-week adaptation each roup were exposed to AMF (0, 25, 50 and 100 <font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">4</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">T espectively) for 17 days, 5 hours a day. In the second protocol the time of exposure extended to 34 days. After experiments rats' blood serums were removed from their blood samples and kept frozen for usage. The results were analyzed by one way- ANOVA statistical method (p < 0.05).</font></font></div></li></font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>RESULTS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Chronic exposures (5h/day for 34 days) to AMFs had no effect on serum's testosterone and LH. But, AMF t 100 </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">4</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">T induced an increase of serum's FSH level in omparison with 25 μT, 50 </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">4</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">T and control groups. In contrast, subchronic AMFs (5 h/day for 17 days) induced a decrease of serum's testosterone in control group in omparison with 25, 50 and 100 </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">4</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">T groups. But these AMFs had no effect on serum's LH and FSH levels.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>CONCLUSIONS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Increased level of FSH suggests damage to the seminiferous tubules. Our results suggest that AMFs probably causes dysfunction in gonadal axis at the hypothalamic-pituitary level in male rats in different protocols.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>KEYWORDS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Sex Hormones, Male Rats, Magnetic Field.</font></font></div></li></font></font></ul></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/2329http://jrms.mui.ac.ir/index.php/jrms/article/download/2329/1669Journal of Research in Medical Sciences1735-199514420090603Clinicopathological significance of E-cadherin, !-catenin and p53 expression in gastric adenocarinoma239247ENResearch center for gastroenterology and Liver Disease (RCgln), Shahid Beheshti University of Medical Sciences, Tehran, IranDivision of Human Genetics, Immunology Research Center, Avicenna Research InstituteDepartment of Pathology, Omid Hospital, MUMS, Mashhad, IranDivision of Human Genetics, Immunology Research Center, Avicenna Research InstituteDepartment of Pathology, Imam-Reza Hospital, MUMS, Mashhad, IranDivision of Human Genetics, Immunology Research Center, Avicenna Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.Division of Human Genetics, Immunology Research Center, Avicenna Research Institute200810092009041820090329<font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><ul><li><div align="left"><strong>BACKGROUND</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">E-cadherin/catenin complexes exert a role in cell adhesion. </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin is a key player in Wnt signaling pathway in gastric cancer. P53 is a tumor suppressor gene which also regulates apoptosis. We assessed the expression of E-cadherin, </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin and p53 in gastric adenocarcinoma, and their correlations with linicopathological features.</font></font></div></li><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>METHODS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Fifty six formalin-fixed, paraffin-embedded archival specimens of gastric adenocarcinoma were andomly included as cases. Adjacent tumor-free gastric mucosa of different premalignant stages was obtained from the cases. Immunohistochemical staining was performed to assess E-cadherin, </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin and p53 expression.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>RESULTS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">All chronic atrophic gastritis and intestinal metaplasia revealed normal membranous staining. Only one patient with dysplasia had abnormal expression of E-cadherin and </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-Catenin. Abnormal E-cadherin, </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin and p53 expression was found in 50%, 48.2% and 76.8% of cancer specimens respectively. Abnormal expression of E-cadherin was significantly correlated with aberrant </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin expression. Abnormal E-cadherin and </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin expression were significantly correlated with depth of tumor invasion and advanced gastric cancer (p < 0.05), lower degree of differentiation and diffused tumor type (p < 0.001). Node metastasis was not influenced by abnormal expression of E-cadherin and </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin. P53 was not associated with clinicopathological variables.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>CONCLUSIONS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Abnormal expression of the E-cadherin and </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin were associated with each other and influenced by histogenesis of gastric cancer and malignant behavior of tumor but not significant in premalignant lesions. They are more frequent in diffuse type and associated with advanced gastric cancer. P53 alterations are more frequent in the Iranian population compared with others.</font></font></div></li></font></font><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>KEYWORDS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Gastric Cancer, E-cadherin, </font></font><font face="+TimesNewRoman" size="2"><font face="+TimesNewRoman" size="2">'</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">-catenin, p53, Immunohistochemistry.</font></font></div></li></font></font></ul></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/2400http://jrms.mui.ac.ir/index.php/jrms/article/download/2400/1746Journal of Research in Medical Sciences1735-199514420090511Prevalence of chronic hepatitis B infection in Iran: a review article249258ENDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Science (TUMS)Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Science (TUMS)2008121320090303<font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2"><ul><li><div align="left">Hepatitis B virus infection is a major public health problem worldwide. Islamic Republic of Iran is a country in which hepatitisB prevalence is intermediate. The aim of this study is to assess prevalence of chronic hepatitis B infection in Iran according to demographic characteristics. All cross-sectional studies concerning revalence of chronic hepatitis B infection in Iran were included irrespective of date and language. The outcome of interest was prevalence of chronic hepatitis B infection confirmed by blood specimen positive for HBsAg. The prevalence of chronic hepatitis B infection was stimated about 1.7% or lower in general population; 0.8% (95% CI: 0.6% to 0.9%) in blood donors and 3.2% (95% CI: 2.3% to 4.1%) in intravenous drug users and varied from zero to 1.5% in beta thalassemic patients. Since mass vaccination in 1993, prevalence of chronic hepatitis B infection has being reduced among children and adolescents. This reduction can be attributed to the effectiveness of the national immunization program and it may impact on reduction of prevalence of hepatitis B infection in general population.</div></li><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>KEY WORDS:</strong> <font face="BookAntiqua" size="2"><font face="BookAntiqua" size="2">Hepatitis B, Prevalence, Blood Donors, Thalassemia, Drug Users, Iran</font></font><font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2"><strong>.</strong></font></font></div></li></font></font></ul></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/2714http://jrms.mui.ac.ir/index.php/jrms/article/download/2714/1745Journal of Research in Medical Sciences1735-199514420090103Traumatic bilateral globe avulsion (case report)259260EN2008110420081229<font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2"><ul><li><div align="left">Avulsion of the globe is a rare event, and there are only a few reports of true total enucleation of the globes in he literature. We report a 20-year-old man who was a victim of car accident, with bilateral enucleation of the globe. This is the third reported case of bilateral subluxated globes that were successfully repositioned in the orbits. Although the patient had no light perception vision, preserving his one eye reduced the psychological stress of sudden traumatic loss of vision for him and his relatives.</div></li><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>KEYWORDS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Globe Avulsion, Traumatic Enucleation.</font></font></div></li></font></font></ul></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/2575http://jrms.mui.ac.ir/index.php/jrms/article/download/2575/1405Journal of Research in Medical Sciences1735-199514420090511Ulcerative colitis and neurofibromatosis type 1 with bilateral psoas muscle neurofibromas: a case report261265ENDepartment of Gastroenterology, Alzahra Hospital, Isfahan University of Medical Sciences (IUMS), Isfahan, IranDepartment of Internal Medicine, Alzahra Hospital, IUMS, Isfahan, IranDepartment of Pathology, Alzahra Hospital, IUMS, Isfahan, IranDepartment of Radiology, Alzahra Hospital, IUMS, Isfahan, Iran200807262009040620090209<font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2"><ul><li><div align="left">The most common gastrointestinal involvement in eurofibromatosis is due to tumoral lesions which may resent with gastrointestinal bleeding or obstruction. We report a case of concurrent ulcerative colitis and eurofibromatosis.A 39 year-old woman, known case of neurofibromatosis, was admitted to our department with complaint of chronic bloody diarrhea. After thorough clinical examination and paraclinical assessments, ncluding colonoscopy and biopsy, ulcerative colitis was confirmed as the cause of gastrointestinal bleeding. Another rare finding in this patient was bilateral neurofibroma in psoas muscle that was detected on abdominal spiral Computer Tomography scan.</div></li><font face="TimesNewRoman,Bold" size="1"><font face="TimesNewRoman,Bold" size="1"><li><div align="left"><strong>KEYWORDS</strong>: <font face="TimesNewRoman" size="2"><font face="TimesNewRoman" size="2">Ulcerative Colitis, Neurofibromatosis, Von Recklinghausen’s Disease, Mast Cells, Bilateral urofibroma, Psoas Muscle.</font></font></div></li></font></font></ul></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/2148http://jrms.mui.ac.ir/index.php/jrms/article/download/2148/1638Journal of Research in Medical Sciences1735-199514420090511Retinal detachment in Isfahan Feiz hospital (an epidemiologic study)267267EN2009011520090421http://jrms.mui.ac.ir/index.php/jrms/article/view/2854http://jrms.mui.ac.ir/index.php/jrms/article/download/2854/1639