Journal of Research in Medical Sciences1735-199515320100104167171ENSkin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Center for Research and Training in Skin Diseases and Leprosy, Medical Sciences/University of Tehran, IranSkin Diseases and Leishmaniasis Research Center, Isfahan University of Medical SciencesSkin Diseases and Leishmaniasis Research Center, Isfahan University of Medical SciencesRooyan Institute, Jahad Daneshgahiskin disease and leishmaniasis research center-isfahan university of medical sciencesRooyan Institute, Jahad Daneshgahi2009061820091103<ul><li><strong><span style="font-size: 8pt;">BACKGROUND:</span></strong> <span class="abstractChar">There are many filler agents for augmentation of static wrinkles and atrophic scars from synthetic, biosynthetic, cadaver, animal and human sources.</span></li><li><strong><span style="font-size: 8pt;">METHODS:</span></strong><strong><span style="font-size: 8pt;"> </span></strong><span class="abstractChar">The current study presents 20 patients whose facial wrinkles and lines were treated by transplantation of autologous cultured fibroblasts. The fibroblast nature of cells was confirmed by immune-staining and flow cytometry.</span></li><li><strong><span style="font-size: 8pt;">RESULTS:</span></strong><span class="abstractChar"> The mean of improvement for this procedure at the 6 month follow up was 41%.</span></li><li><strong><span style="font-size: 8pt;">CONCLUSIONS:</span></strong><span class="abstractChar"> In conclusion autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars.</span></li><li><strong><span style="font-size: 8pt; font-family: &quot;Times New Roman&quot;;">KEYWORDS: </span></strong><span class="abstractChar"><span style="font-size: 12pt; font-family: &quot;Times New Roman&quot;;">Soft Tissue Augmentation, Fibroblast, Wrinkle</span></span></li></ul><!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> </w:WordDocument> </xml><![endif]--><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState="false" LatentStyleCount="156"> </w:LatentStyles> </xml><![endif]--> <!--[endif]-->http://jrms.mui.ac.ir/index.php/jrms/article/view/3908http://jrms.mui.ac.ir/index.php/jrms/article/download/3908/1963