Journal of Research in Medical Sciences1735-1995642001120134433443ENDepartment of Neurosurgery, School of Medicine,Isfahan Uni. of Medical Sciences and Health Services, Isfahan, Iran.of Iran2001120120090411Introduction: There is no definite acceptible method for cranioplasty among neurosergens, yet. We examined Mersilene Mesh for cranioplasty and evaluate its efficacy. Methods: Forty traumatic patients with cranial depressed fracture were studied. They were divided two group randomly. Interventional group was treated by Madrilène Mesh. Cranial fractured bones were sutured to each other with silk. Patients were followed in 1, 3, 6 and 12 month continually. Results: Only two patients in interventional group and seven patients in control group had some looseness in cranial bone after 9 months follow up (P < 0.05). There was no evidence of infection, graft rejection and wound dehisence in two groups. Discussion: It seems that Mersilene mesh use in cranioplasty is effective and useful.http://jrms.mui.ac.ir/index.php/jrms/article/view/3443