Journal of Research in Medical Sciences1735-1995612001030133073307ENDepartment of Infectious and Tropical Disease, School of Medicine, School of Medicine, Isfahan University of Medical Sciences and Health Services, Isfahan2001030120090330<font><font color="#555555"><span style="font-size: 10pt; font-family: Tahoma">Introduction. Central nervous system infections are among the most serious conditions in of medical practice. C-reactive Protein has recently been evaluated in terms of its ability to diffeccentiate bacterial from nonbacterial central nervous system inflammations. <br />Methods. We studied the frequency of positive CRP in 61 patients who had signs of meningitis. All the specimens referred to one laboratory and were examined by Slide method. <br />Results. Positive CRP was found in 97.6 percent of those who were finally diagnosed as bacterial meningitis. The frequency of CRP for other types of meningitis was 16.6 percent (P < 0.05).<br />Discussion. In the absence of infection, CSF is free of CRP. Positive CRP may help to the differentiate the different types of meningitis.</span></font></font>http://jrms.mui.ac.ir/index.php/jrms/article/view/3307