Pulmonary Alveolar Proteinosis in Children: A case series

Journal of Research in Medical Sciences1735-199515220100104Pulmonary Alveolar Proteinosis in Children: A case series120124ENAssistant Professor of Pediatrics, Mofid Children Hospital, Shaheed Beheshti Medical University, Tehran, IRANProfessor of pediatric infectious diseasesAssistant Professor of Pediatrics, Pediatric Infectious Research Center, Mofid Children Hospital, Shaheed Beheshti Medical University, Tehran, IRANAssistant Professor of Anesthesiology, Shaheed Moddares Hospital, Shaheed Beheshti Medical University, Tehran, IRANAssistant Professor of Pathology, Pediatric Infectious Research Center, Mofid Children Hospital, Shaheed Beheshti Medical University, Tehran, IRANAssociate Professor of Pediatrics, Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti Medical University, Tehran, IranGeneral Practitioner, Researcher, Pediatric Infections Research Center, Shahid Beheshti University,Tehran, Iran.2008122020091104<ul><li>Pulmonary alveolar proteinosis, (PAP) is a rare disease of unknown etiology, characterized by accumulation of intra-alveolar proteinaceous material which is rich in lipid and positive on periodic acid-Schiff stain. Two clinically different pediatric types have been defined as congenital PAP which is fulminant and fatal, and a late-onset PAP which is similar to the adult form and less severe. Eight children with late-onset PAP were hospitalized from 1998 to 2005 in Mofid Children Hospital. Characteristics of these patients and the methods of diagnosis and treatment are presented in this case series.</li><li><strong><span style="font-size: 8pt;">KEYWORDS: </span></strong>Pulmonary Alveolar Proteinosis, Respiratory Failure, Respiratory Distress, Children.</li></ul>    http://jrms.mui.ac.ir/index.php/jrms/article/view/2744http://jrms.mui.ac.ir/index.php/jrms/article/download/2744/1876