Journal of Research in Medical Sciences1735-1995232201802241075910759EN1, 2, 3,20180224<span class="fontstyle0">Background: </span><span class="fontstyle2">This study aimed to compare the effects of combined endurance?resistance training (CT) versus endurance training (ET) on some cardiovascular markers in patients with heart failure after percutaneous coronary intervention (PCI). </span><span class="fontstyle0">Materials and Methods: </span><span class="fontstyle2">Te study applied a randomized, controlled design in which 75 patients with heart failure who had undergone PCI were randomly assigned to one of three groups: ET, CT, and control. Te ET group performed ET for 45 min, three times a week for 7 weeks. Te CT group performed the same ET for 30 min followed by a resistance exercise protocol. Te control group received usual care.  Functional capacity, N?terminal pro?brain natriuretic peptide (NT?pro BNP), and high sensitivity C?reactive protein (hs?CRP) levels were measured. </span><span class="fontstyle0">Results: </span><span class="fontstyle2">After the intervention, functional capacity was improved (</span><span class="fontstyle3">P </span><span class="fontstyle2">&lt;  0.001) and NT?pro BNP level was signifcantly reduced (</span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.004 in the CT group, </span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.002 in the ET group). Hs?CRP level was signifcantly reduced only in the ET group (</span><span class="fontstyle3">P </span><span class="fontstyle2">= 0.030). Te control group showed no signifcant changes in any cardiovascular parameters (</span><span class="fontstyle3">P </span><span class="fontstyle2">? 0.05). Changes in<br />functional capacity (</span><span class="fontstyle3">P </span><span class="fontstyle2">&lt; 0.001) in both training groups were signifcantly di?erent from the control group. No signifcant di?erences were found between the ET and CT groups regarding changes in all outcomes after exercise training (</span><span class="fontstyle3">P </span><span class="fontstyle2">? 0.05). </span><span class="fontstyle0">Conclusion: </span><span class="fontstyle2">Exercise training is safe and feasible in post?PCI patients, even in those with reduced ejection fraction. CT was as e?ective as ET in reducing NT?pro BNP level and improving functional capacity in heart failure patients after PCI.</span> <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10759http://jrms.mui.ac.ir/index.php/jrms/article/download/10759/5600