Journal of Research in Medical Sciences1735-1995231201802031075310753EN20180203<span class="fontstyle0">We carried out this meta?analysis for the aim of exploring the in?uence of diabetes mellitus (DM) on the prognosis of patients with<br />ischemic stroke. Relevant studies were identifed using computerized databases supplemented with manual search strategies. Te<br />included studies were strictly followed the inclusion and exclusion criteria. Case?control studies which related to the in?uence of DM<br /></span><table class="NormalTable"><tbody><tr><td width="550"><span class="fontstyle0">on the prognosis of patients with ischemic stroke were selected. Statistical analyses were implemented with the STATA version 12.0<br />statistical software. Our current meta?analysis initially retrieved 253 studies (227 in Chinese and 26 in English), 13 studies (6 in<br />English and 7 in Chinese) were eventually incorporated in this meta?analysis. Tese 13 case?control studies included 8463 patients<br />altogether (3249 patients with DM complicated with ischemic stroke and 5214 patients with ischemic stroke). Te results of this<br />meta?analysis manifested that there was a signifcant di?erence of the blood glucose level at 48 h after stroke between patients with DM complicated with ischemic stroke and patients with ischemic stroke  standard mean di?erence [SMD] =1.27, 95% confdence interval [CI] =0.02–2.51, </span><span class="fontstyle2">P </span><span class="fontstyle0">= 0.047); however, the e?ectiveness, fatality, and the  National Institutes of Health Stroke Scale (NIHSS) score in patients with DM complicated with ischemic stroke, and patients with ischemic stroke had no signifcant di?erence (e?ectiveness: risk ratio [RR] = 0.88, 95% CI = 0.75–1.03, </span><span class="fontstyle2">P </span><span class="fontstyle0">= 0.121; fatality: RR = 1.29, 95% CI = 0.97–1.71, </span><span class="fontstyle2">P </span><span class="fontstyle0">= 0.081; NIHSS score: SMD = -0.14, 95% CI = -1.56?1.28, </span><span class="fontstyle2">P </span><span class="fontstyle0">= 0.849). Te current evidence suggests that there is statistical di?erence of the blood glucose level at 48 h after stroke between patients with DM complicated with ischemic stroke and patients with ischemic stroke, but there is no statistical di?erence of prognostic indicators between patients in two groups. Tus, our study provides certain clinical value.<br /></span></td></tr></tbody></table> <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10753http://jrms.mui.ac.ir/index.php/jrms/article/download/10753/5594