Prevalence and antibiotic resistance pattern of bacteria isolated from urinary tract infections in Northern Iran

Journal of Research in Medical Sciences1735-199522920170927Prevalence and antibiotic resistance pattern of bacteria isolated from urinary tract infections in Northern Iran1069110691EN20170724Background: Tis study aimed to investigate the bacteria associated with urinary tract infection (UTI) and antibiotic susceptibility pattern of the isolates during 2013–2015 in Northern Iran. Materials and Methods: Overall 3798 patients with clinical symptoms of UTI were subjected as samples, and they were cultured and pure isolated bacteria were identifed using biochemical tests and subjected to antibiogram assessment using disc di?usion method. Results: Totally, 568 (14.96%) from 3798 patients had positive UTI. Four hundred and ninety?seven (87.5%) from 568 isolated bacteria were resistant to at least one antibiotic. Escherichia coli, Staphylococcus spp., and Pseudomonas spp. were the most prevalent bacteria. Isolated bacteria indicated the highest antibiotic resistance to methicillin (76.06%) and ampicillin (89.29%) and also revealed the most sensitivity to imipenem (99.1%) and amikacin (91.57%). Statistical analysis of the resistance pattern trend during 3 years indicated the insignifcant increase (P > 0.05) in antibiotic resistance of the isolates. Conclusion: Te results of this study revealed a great concern for emerging UTI?related multidrug?resistant strains of bacteria causing UTI in Iran. <br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" />http://jrms.mui.ac.ir/index.php/jrms/article/view/10691http://jrms.mui.ac.ir/index.php/jrms/article/download/10691/5548