Journal of Research in Medical Sciences1735-199517120120114Attitude scale and general health questionnaire subscales predict depression?74327432ENAmrollahEbrahimiAssistant Professor, Behavioral Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. a_ebrahimi@med.mui.ac.irHamidAfsharHamidTaherNeshat DoostSeyed GhafurMousaviHoseynMoolavi2011080420120113BACKGROUND: According to Beck theory, dysfunctional attitude has a central role in emergence of depression. The aim of this study was to determine contributions of dysfunctional attitude and general health index to depression. METHODS: In this case-control study, two groups of subjects participated. The first group consisted of 65 patients with major depression and dysthymic disorder, who were recruited from Noor and Navab Safavi Psychiatry Clinics in Isfahan. The control group was consisted of 65 non-patient individuals who were accompanied or relatives of the patients and was matched with them based on age, sex and education. Both groups completed 26-item Dysfunctional Attitude Scale (DAS-26) and 28-item General Health Questionnaire (GHQ-28). Logistic regression and correlation methods were applied for statistical analysis. RESULTS: Logistic regression analysis showed that by an increase of one level in categorized DAS-26 scores and one score in the physical symptoms, anxiety, social dysfunction and depression subscales of GHQ-28 the risk of depression increase by 6.8, 1.6, 1.9, 3.7, 4.78 times, respectively. CONCLUSIONS: Capability of dysfunctional attitude and general health subscales to predict depression supports the Beck's cognitive diathesis stress theory of depression that dysfunctional attitude may be a predisposing risk factor for depression. KEYWORDS: Depression, Beliefs, Cognition, Dysfunctional Attitude, General Health