Journal of Research in Medical Sciences1735-199516620110616Evaluation of accuracy of Euroscore risk model in prediction of perioperative mortality after coronary bypass graft surgery in Isfahan, Iran69356935ENMohsenMirmohammad SadeghiMahfarArastehMojganGharipourResearcher in Clinical Biochemistry, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran. gharipour@crc.mui.ac.irPeymanNilfroushHamidShamsolketabiAliEtesampourFatemehMirmohammad SadeghiAmjadKianiPouyaMirmohammad SadeghiNiloufarFarahmand201103092011061320110611BACKGROUND: This study aimed to evaluate the accuracy of Euroscore (European System for Cardiac Operative Risk Evaluation) in predicting perioperative mortality after cardiac surgery in Iranian patient population.METHODS: Data on 1362 patients undergoing coronary bypass graft surgery (CABG) from 2007 to 2009 were collected. Calibration was assessed by Hosmer-Lemeshow goodness-of-fit. Area under the curve (AUC) was used to assess score validity. Odds ratios were measured to evaluate the predictive value of each risk factor on mortality rate.RESULTS: The overall perioperative in hospital mortality was 3.6% whereas the Euroscore predicted a mortality of 3.96%. Euroscore model fitted well in the validation databases. The mean AUC was 66%. Mean length of intensive care unit (ICU) stay was 2.5 ± 2.5 days. Among risk factors, only left ventricular dysfunction, age and neurologic dysfunction were found to be related to mortality rate.CONCLUSIONS: Euroscore did not have acceptable discriminatory ability in perioperative in hospital mortality in Iranian patients. It seems that development of a local mortality risk scores corresponding to our patients epidemiologic characteristics may improve prediction of outcome.KEYWORDS: Euroscore Model, Hospital, Mortality, Preoperative, Cardiac Surgery.