Journal of Research in Medical Sciences1735-199517220120215The relation of obesity with serum resistin levels in smoker and nonsmokers69186918ENGülGürsoyAssociate Professor, Department of Internal Medicine, Ministry of Health, Ankara Education and Research Hospital, Ankara, Turkey. gulgursoyyener@yahoo.comOnurEşbahNazliGülsoyKirnapHacerÇetinerYaşarAcarBerrinDemirbaşAbidinÖztürkZuhalKiliç2011030720110704BACKGROUND: The demonstration that adipose tissue produces numerous  cytokines increases interest of investigators in their role in the pathogenesis of obesity. Resistin is one of those cytokines. There are conflicing reports as cigarette smoking impairs insulin secretion, augments insulin resistance, or has no effect on glucose metabolism. In our study, we intended to examine the relationship of obesity with resistin levels in smokers and nonsmokers. METHODS: The study included 52 male smokers and 34 age matched  nonsmoker  male control  subjects. We classified smoker and nonsmoker  groups according to their body mass index as BMI < 27 and ≥27. As well as making physical and anthropometric examinations, fasting plasma glucose and insulin, postprandial plasma glucose, lipid profile, and resistin levels were measured  in all male subjects. We compared  all parameters  in smoker and nonsmokers either having BMI < 27 or ≥ 27. RESULTS: In both BMI levels, resistin levels were higher in smoker groups than nonsmoker ones (p < 0.01 all), we did not find any difference in other parameters. CONCLUSION: in conclusion we may speculate that if someone smokes resistin levels increase.KEYWORDS: Obesity, Resistin, Smoking