Journal of Research in Medical Sciences1735-199517320120311Effect of turbinoplasty in concha bullosa induced rhinogenic headache, a randomized clinical trial68076807ENMohammad EbrahimYarmohammadiHassanGhasemiAssociate Professor, Department of Ophthalmology, School of Medicine, Shahed University, Tehran, Iran. ghasemi518@yahoo.comShahryarPourfarzamMohammad RezaJalali NadoushanSiamakAfshin Majd2011021520120126BACKGROUND: Rhinogenic origin is an important source for headache, which may be treated by medical or endoscopic intervention. An aim of this study was to clarify whether the surgical or medical intervention is superior. METHODS: In this randomized double blind clinical trial study, 44 patients (19 male and 25 female) with periorbital or frontal pain were enrolled. Patients were divided into 2 groups of surgical or medical intervention randomly. Medical group received 3 courses of 1.5 months 125 μg per puff, fluticason nasal spray (2 puffs Q 24 hours in each side), and oral Pseudoephedrin 30 mg Q 8 hours with 2 weeks intervals. Surgical group underwent turbinoplasty with functional endoscopic sinus surgery approach. Duration (per hour), frequency (per week) and severities of the headaches were measured by Visual Analog Scale (VAS) before treatment, and at 1.5, 3 and 6 months after institution of treatment by an examiner, who was unaware of the patients’ treatment plan. RESULTS: Before treatment, chronicity (P = 0.980), severity (P = 0.742), frequency (P = 0.730), and duration (P = 0.603) of the headaches were not significantly different. The severities of the headaches in surgical group were significantly lower at 1.5, 3 and 6 months (P < 0.001), also the frequencies and the durations of the headaches were significantly lower at 6 months after an institution of treatment compared to medical group (P = 0.027, P = 0.008, respectively). CONCLUSION: Turbinoplasty in chonca bullusa patients is an acceptable and a simple procedure for relieving pain in rhinogenic headaches, compared with medical treatment. KEYWORDS: Concha bullusa, endoscopic intervention, frontal pain, medical treatment, periorbital pain, rhinoigenic headache, surgical treatment, turbinoplast