Journal of Research in Medical Sciences1735-199514420090511Ulcerative colitis and neurofibromatosis type 1 with bilateral psoas muscle neurofibromas: a case report261265ENHamidTavakkoliDepartment of Gastroenterology, Alzahra Hospital, Isfahan University of Medical Sciences (IUMS), Isfahan, Iran. h_tavakoli@med.mui.ac.irMehrnazAsadiParvinMahzouniAbdolaliForoozmehr200807262009040620090209The most common gastrointestinal involvement in  eurofibromatosis is due to tumoral lesions which may  resent with gastrointestinal bleeding or obstruction. We report a case of concurrent ulcerative colitis and  eurofibromatosis.A 39 year-old woman, known case of neurofibromatosis, was admitted to our department with complaint of chronic bloody diarrhea. After thorough clinical examination and paraclinical assessments,  ncluding colonoscopy and biopsy, ulcerative colitis was confirmed as the cause of gastrointestinal bleeding. Another rare finding in this patient was bilateral neurofibroma in psoas muscle that was detected on abdominal spiral Computer Tomography scan.KEYWORDS: Ulcerative Colitis, Neurofibromatosis, Von Recklinghausen’s Disease, Mast Cells, Bilateral   urofibroma, Psoas Muscle.